Article
TT genotype of transforming growth factor beta1 +869C/T is associated with the development of chronic kidney disease after liver transplantation.
Transplantation proceedings - 1 Nov 2014
Cuenca A B, Citores M J, de la Fuente S, Duca A M, Escamilla N, Baños I, Cuervas-Mons V
Abstract excerpt
BACKGROUND: Chronic kidney disease (CKD) is a frequent complication in patients with liver transplantation (LT), and calcineurin inhibitor chronic nephrotoxicity, mediated by transforming growth factor beta1 (TGF-β1) is an important contributing factor. The aim of this study was to assess the influence of genetic polymorphisms of TGF-β1 in the development of CKD at 6 months after transplantation. METHODS: One...
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