Article
ERCC6/CSB gene polymorphisms and lung cancer risk.
Cancer letters - 8 Jan 2009
Ma Hongxia, Hu Zhibin, Wang Haifeng, Jin Guangfu, Wang Ying, Sun Weiwei, Chen Dan, Tian Tian, Jin Li, Wei Qingyi, Lu Daru, Huang Wei, Shen Hongbing
Abstract excerpt
Nucleotide excision repair (NER) enzymes are critical for the removal of bulky DNA adducts caused by environmental carcinogens such as smoking. Of them, Cockayne syndrome complementation group B (CSB), coded by ERCC6, recruits NER repair factors to the DNA damage site and plays an important role...
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