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Article

Sequence variations in DNA repair gene XPC is associated with lung cancer risk in a Chinese population: a case-control study.

BMC cancer - 13 May 2007

Bai Yun, Xu Liang, Yang Xiaobo, Hu Zhibin, Yuan Jing, Wang Feng, Shao Minhua, Yuan Wentao, Qian Ji, Ma Hongxia, Wang Ying, Liu Hongliang, Chen Weihong, Yang Lin, Jing Guangfu, Huo Xiang, Chen Feng, Liu Yanhong, Jin Li, Wei Qingyi, Huang Wei, Shen Hongbing, Lu Daru, Wu Tangchun

Abstract excerpt

BACKGROUND: The nucleotide excision repair (NER) protein, xeroderma pigmentosum C (XPC), participates in recognizing DNA lesions and initiating DNA repair in response to DNA damage. Because mutations in XPC cause a high risk of cancer in XP patients, we hypothesized that inherited sequence variations in XPC may alter DNA repair and thus susceptibility to cancer. METHODS: In this hospital-based case-control study,...

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Identifiers

PMID: 17498315
DOI: 10.1186/1471-2407-7-81
PMCID: PMC1884164

Genes

XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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