Article
Association of DNA double-strand break gene XRCC6 genotypes and lung cancer in Taiwan.
Anticancer research - 1 Mar 2012
Hsia Te-Chun, Liu Chin-Jung, Chu Chia-Chen, Hang Liang-Wen, Chang Wen-Shin, Tsai Chia-Wen, Wu Chao-I, Lien Chi-Shun, Liao Wen-Ling, Ho Chien-Yi, Bau Da-Tian
Abstract excerpt
AIM: The DNA repair gene X-ray repair complementing defective repair in Chinese hamster cells 6 (XRCC6) is thought to play an important role in the repair of DNA double-strand breaks. It is known that defects in double-strand break repair capacity can lead to irreversible genomic instability. However, the association of polymorphic variants of XRCC6 with lung cancer susceptibility has never been reported. In this...
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