Imprinting mechanisms in mammals.

Abstract excerpt

Imprinting is a genetic mechanism that determines expression or repression of genes according to their parental origin. Some imprinted genes occur in clusters in the genome. Recent work using transgenic mice shows that multiple cis-acting sequences are needed for correct imprinting. Mutation analysis in a normal chromosomal context reveals the importance of imprinting centres for regional establishment or...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Germ Cells
• Share to Mammals
• Share to Mice