Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Imprinted expression of neuronatin from modified BAC transgenes reveals regulation by distinct and distant enhancers.

Developmental biology - 15 Aug 2001

John R M, Aparicio S A, Ainscough J F, Arney K L, Khosla S, Hawker K, Hilton K J, Barton S C, Surani M A

Abstract excerpt

Neuronatin (Nnat) is an imprinted gene that is expressed exclusively from the paternal allele while the maternal allele is silent and methylated. The Nnat locus exhibits some unique features compared with other imprinted domains. Unlike the majority of imprinted genes, which are organised in clusters and coordinately regulated, Nnat does not appear to be closely linked to other imprinted genes. Also unusually,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Choristoma
Share to Chromosomes, Artificial, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enhancer Elements, Genetic

Share to Genomic Imprinting

Share to In Situ Hybridization

Share to Introns

Share to Nerve Tissue Proteins

Share to Transgenes

Source

Identifiers

PMID: 11476579
DOI: 10.1006/dbio.2001.0327

Genes

NNAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Imprinted expression of neuronatin from modified BAC transgenes reveals regulation by distinct and distant enhancers.PMID 11476579Read ↗

The neuronatin gene resides in a "micro-imprinted" domain on human chromosome 20q11.2.Semantic proximity Read ↗

An intronic DNA sequence within the mouse Neuronatin gene exhibits biochemical characteristics of an ICR and acts as a transcriptional activator in Drosophila.Semantic proximity Read ↗

Neuronatin gene: Imprinted and misfolded: Studies in Lafora disease, diabetes and cancer may implicate NNAT-aggregates as a common downstream participant in neuronal loss.Semantic proximity Read ↗

A cis-acting control region is required exclusively for the tissue-specific imprinting of Gnas.Semantic proximity Read ↗

Genetic and functional analysis of neuronatin in mice with maternal or paternal duplication of distal Chr 2.Semantic proximity Read ↗

Monoallelic gene expression in mammals.Semantic proximity Read ↗

Control of imprinting at the Gnas cluster.Semantic proximity Read ↗

The mouse Necdin gene is expressed from the paternal allele only and lies in the 7C region of the mouse chromosome 7, a region of conserved synteny to the human Prader-Willi syndrome region.Semantic proximity Read ↗

Neuronatin deletion causes postnatal growth restriction and adult obesity in 129S2/Sv miceSemantic proximity Read ↗

A mono-allelic bivalent chromatin domain controls tissue-specific imprinting at Grb10.Semantic proximity Read ↗

The imprinted gene neuronatin is regulated by metabolic status and associated with obesity.Semantic proximity Read ↗

Role of DNA Methylation and Histone H3 Lysine 27 Methylation in Tissue-Specific Imprinting of Mouse Grb10Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.