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Article

A length polymorphism in the circadian clock gene Per3 influences age at onset of bipolar disorder.

Neuroscience letters - 14 Nov 2008

Benedetti Francesco, Dallaspezia Sara, Colombo Cristina, Pirovano Adele, Marino Elena, Smeraldi Enrico

Abstract excerpt

Age at onset of bipolar disorder might represent the penetrance of the system for specific genetic liability involved in the genesis of the illness. Genetic factors influencing age at onset have been shown to play a role in shaping core characteristics of the illness, such as severity and pattern of recurrence. Genetic variants of genes regulating the circadian clock could contribute to define endophenotypes of...

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PMID: 18789374
DOI: 10.1016/j.neulet.2008.09.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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