Article
Circadian clock gene Per3 variants influence the postpartum onset of bipolar disorder.
European psychiatry : the journal of the Association of European Psychiatrists - 1 Apr 2011
Dallaspezia S, Lorenzi C, Pirovano A, Colombo C, Smeraldi E, Benedetti F
Abstract excerpt
Postpartum depression can mark the onset of bipolar disorder. The coding region of Per3 gene contains a variable-number tandem-repeat polymorphism, which has been shown to influence bipolar disorder onset and to affect breast cancer risk. We showed a relationship between Per3 polymorphism and postpartum depressive onset in bipolar disorder.
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