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Article

Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2006

Nievergelt Caroline M, Kripke Daniel F, Barrett Thomas B, Burg Elyssa, Remick Ronald A, Sadovnick A Dessa, McElroy Susan L, Keck Paul E, Schork Nicholas J, Kelsoe John R

Abstract excerpt

Bipolar affective disorder (BPAD) is suspected to arise in part from malfunctions of the circadian system, a system that enables adaptation to a daily and seasonally cycling environment. Genetic variations altering functions of genes involved with the input to the circadian clock, in the molecula...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16528748
DOI: 10.1002/ajmg.b.30252
PMCID: PMC2651679

Genes

PER3
CLOCK
CRY2
DBP
NPAS2
PER1
PER2
PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16528748-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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