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Article

Replication of genetic information with self-encoded replicase in liposomes.

Chembiochem : a European journal of chemical biology - 13 Oct 2008

Kita Hiroshi, Matsuura Tomoaki, Sunami Takeshi, Hosoda Kazufumi, Ichihashi Norikazu, Tsukada Koji, Urabe Itaru, Yomo Tetsuya

Abstract excerpt

In all living systems, the genome is replicated by proteins that are encoded within the genome itself. This universal reaction is essential to allow the system to evolve. Here, we have constructed a simplified system involving encapsulated macromolecules termed a "self-encoding system", in which the genetic information is replicated by self-encoded replicase in liposomes. That is, the universal reaction was...

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PMID: 18785673
DOI: 10.1002/cbic.200800360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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