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Article

Adaptation and Diversification of an RNA Replication System under Initiation- or Termination-Impaired Translational Conditions.

Chembiochem : a European journal of chemical biology - 1 Jul 2016

Mizuuchi Ryo, Ichihashi Norikazu, Yomo Tetsuya

Abstract excerpt

Adaptation to various environments is a remarkable characteristic of life. Is this limited to extant complex living organisms, or is it also possible for a simpler self-replication system to adapt? In this study, we addressed this question by using a translation-coupled RNA replication system that comprised a reconstituted translation system and an RNA "genome" that encoded a replicase gene. We performed RNA...

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PMID: 27038303
DOI: 10.1002/cbic.201600100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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