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Article

Hepatic Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) regulates metabolism in mice.

PloS one - 1 Jan 2017

Scott Christopher H, Cha Kuan-Minn, Ngai Jason, Jiang Changtao, Cheng Kim, Stokes Rebecca A, Ho Kenneth W K, George Jacob, Gonzalez Frank J, Gunton Jenny E

Abstract excerpt

BACKGROUND & AIMS: Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) and its partners hypoxia-inducible factors (HIF)-1α and HIF-2α are candidate factors for the well-known link between the liver, metabolic dysfunction and elevation in circulating lipids and glucose. Methods: Hepatocyte-specific ARNT-null (LARNT), HIF-1α-null (LHIF1α) and HIF-2α-null (LHIF2α) mice were created. RESULTS: LARNT mice had...

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Identifiers

PMID: 29190746
DOI: 10.1371/journal.pone.0186543
PMCID: PMC5708799

Genes

ARNT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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