Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activating SIRT1: a new strategy to prevent atherosclerosis?

16 Jul 2008

Abstract excerpt

The development of atherosclerosis is a complex, multi-step process, which is at least in part controlled by the functional state of the vascular endothelium. It is generally believed that the functional state of the endothelium is influenced by a broad set of cardiovascular risk factors and that endothelial dysfunction is the stereotypic cellular response to a broad range of different stimuli on the background...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18784217
DOI: 10.1093/cvr/cvn245

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activating SIRT1: a new strategy to prevent atherosclerosis?PMID 18784217Read ↗

Endothelial SIRT1 as a Target for the Prevention of Arterial Aging: Promises and ChallengesSemantic proximity Read ↗

The Multifaceted Role of Endothelial Sirt1 in Vascular Aging: An UpdateSemantic proximity Read ↗

Sirtuin 1 in Endothelial Dysfunction and Cardiovascular AgingSemantic proximity Read ↗

Emerging roles of SIRT1 in vascular endothelial homeostasisSemantic proximity Read ↗

SIRT1/eNOS Axis as a Potential Target against Vascular Senescence, Dysfunction and AtherosclerosisSemantic proximity Read ↗

Regulation of SIRT1 by Oxidative Stress-Responsive miRNAs and a Systematic Approach to Identify Its Role in the EndotheliumSemantic proximity Read ↗

Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotype.Semantic proximity Read ↗

SIRT6 in Vascular Diseases, from Bench to BedsideSemantic proximity Read ↗

SIRT6 protects against endothelial dysfunction and atherosclerosis in miceSemantic proximity Read ↗

Role of histone deacetylase Sirt3 in the development and regression of atherosclerosisSemantic proximity Read ↗

The Endothelium as a Target for Anti-Atherogenic Therapy: A Focus on the Epigenetic Enzymes EZH2 and SIRT1Semantic proximity Read ↗

The Role of Sirtuin-1 (SIRT1) in the Physiology and Pathophysiology of the Human PlacentaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.