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Article

Comprehensive genetic characterization of hereditary breast/ovarian cancer families from Slovakia.

Breast cancer research and treatment - 1 Feb 2011

Konecny Michal, Milly Miriam, Zavodna Katarina, Weismanova Eva, Gregorova Jaroslava, Mlkva Iveta, Ilencikova Denisa, Kausitz Juraj, Bartosova Zdena

Abstract excerpt

Germline mutations in the BRCA1/2 genes account for the majority of hereditary breast ovarian cancer (HBOC). Identification of causal mutations may have significant impact on clinical management of such families. Despite high mutation detection rate, many HBOC cases remain without identified cause. These cases warrant use of several analysis methods, such as those for large genomic rearrangements and DNA copy...

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Source

Identifiers

PMID: 21203900
DOI: 10.1007/s10549-010-1325-x

Genes

BRCA1
BRCA2
CHEK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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