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Article

The occurrence of germline BRCA1 and BRCA2 sequence alterations in Slovenian population.

BMC medical genetics - 14 Jan 2011

Stegel Vida, Krajc Mateja, Zgajnar Janez, Teugels Erik, De Grève Jacques, Hočevar Marko, Novaković Srdjan

Abstract excerpt

BACKGROUND: the BRCA1 and BRCA2 mutation spectrum and mutation detection rates according to different family histories were investigated in 521 subjects from 322 unrelated Slovenian cancer families with breast and/or ovarian cancer. METHODS: the BRCA1 and BRCA2 genes were screened using DGGE, PTT, HRM, MLPA and direct sequencing. RESULTS: eighteen different mutations were found in BRCA1 and 13 in BRCA2 gene....

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Source

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Identifiers

PMID: 21232165
DOI: 10.1186/1471-2350-12-9
PMCID: PMC3025939

Genes

BRCA1
BRCA2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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