Article
Structural and functional analysis of NF-kappa B. Determinants of DNA binding specificity and protein interaction.
The Journal of biological chemistry - 23 Dec 1994
Schmid R M, Liptay S, Betts J C, Nabel G J
Abstract excerpt
The NF-kappa B transcription factors display a high degree of sequence conservation in a domain initially described in the rel oncogene. Two family members, NF-kappa B1 and NF-kappa B2, have distinct DNA binding properties and functionally distinct effects on different enhancers. NF-kappa B1, for...
Topics
- Base Sequence
- Cells, Cultured
- DNA
- Humans
- Molecular Sequence Data
- Mutation
- NF-kappa B
- Protein Binding
- Protein Conformation
- Transcription, Genetic
- Tumor Cells, Cultured