Article
Inhibition of transcription factors belonging to the rel/NF-kappa B family by a transdominant negative mutant.
The EMBO journal - 1 Jul 1991
Logeat F, Israël N, Ten R, Blank V, Le Bail O, Kourilsky P, Israël A
Abstract excerpt
The KBF1 factor, which binds to the enhancer A located in the promoter of the mouse MHC class I gene H-2Kb, is indistinguishable from the p50 DNA binding subunit of the transcription factor NF-kappa B, which regulates a series of genes involved in immune and inflammatory responses. The KBF1/p50 f...
Topics
- Animals
- Base Sequence
- CD4-Positive T-Lymphocytes
- Cell Line
- Chromosome Deletion
- Enhancer Elements, Genetic
- Genes, Dominant
- HIV Long Terminal Repeat
- Humans
- Mice
- Molecular Sequence Data
- Mutation