Article
Genomic organization of the gene encoding the p65 subunit of NF-kappa B: multiple variants of the p65 protein may be generated by alternative splicing.
Human molecular genetics - 1 Nov 1993
Deloukas P, van Loon A P
Abstract excerpt
Transcription factor NF-kappa B represents a family of closely related homo- and heterodimeric factors. The most abundant form of NF-kappa B is the p50/p65 heterodimer. We determined the complete genomic structure of the human gene and a partial structure of the mouse gene encoding p65. The human...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- DNA
- DNA Primers
- DNA, Neoplasm
- Exons
- Genetic Variation
- Humans
- Introns
- Leukemia, Promyelocytic, Acute
- Macromolecular Substances
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Multigene Family