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Article

A mutant Rel-homology domain promotes transcription by p50/NFkappaB1.

Oncogene - 3 Apr 1997

Xu X, Gélinas C

Abstract excerpt

Previous studies showed that the binding of p50/NFkappaB1 to particular kappaB DNA sites altered its conformation in a way that correlated with transcriptional activation. Here, we investigated the effects of protein-protein interactions on the transcriptional activity of p50. We show that the as...

Topics

Animals
Binding Sites
COS Cells
Mice
Mutagenesis, Site-Directed
Mutation
NF-kappa B
NF-kappa B p50 Subunit
Protein Conformation
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-rel
Transcription Factors
Transcriptional Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transfection

Source

Identifiers

PMID: 9129142
DOI: 10.1038/sj.onc.1200985

Genes

RHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9129142-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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A mutant Rel-homology domain promotes transcription by p50/NFkappaB1.PMID 9129142Read ↗

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