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Article

Glucocorticoids regulate the human occludin gene through a single imperfect palindromic glucocorticoid response element.

Molecular and cellular endocrinology - 25 Nov 2008

Harke Nina, Leers Jörg, Kietz Silke, Drenckhahn Detlev, Förster Carola

Abstract excerpt

The 65kDa protein occludin is an essential element of the blood-brain barrier. This integral membrane protein represents an important part of the tight junctions, which seal and protect the blood brain barrier against paracellular diffusion of solutes to the brain parenchyme and are therefore responsible for the high resistance and low permeability between cerebral capillary endothelial cells. However, the...

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PMID: 18782596
DOI: 10.1016/j.mce.2008.08.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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