Article
Effects of variation status and enzyme activity for UDP-glucuronosyltransferase 1A1 gene on neonatal hyperbilirubinemia.
Pediatrics and neonatology - 1 Oct 2020
Huang May-Jen, Lin Yu-Cheng, Liu Kevin, Chang Pi-Feng, Huang Ching-Shan
Abstract excerpt
BACKGROUND: We found that Taiwanese adults carrying genotypes of UDP-glucuronosyltransferase (UGT) 1A1 with enzyme activity ≤40% of normal were at high risk for developing Gilbert's syndrome. However, the relationship between UGT1A1 activity and neonatal hyperbilirubinemia has never been evaluated for Taiwanese. METHODS: We enrolled 141 hyperbilirubinemic neonates partially fed supplementary infant formula and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
