Article
Genetic polymorphisms of bilirubin uridine diphosphate-glucuronosyltransferase gene in Japanese patients with Crigler-Najjar syndrome or Gilbert's syndrome as well as in healthy Japanese subjects.
Journal of gastroenterology and hepatology - 1 Sept 2004
Takeuchi Keisuke, Kobayashi Yoshinao, Tamaki Shigenori, Ishihara Tomoaki, Maruo Yoshihiro, Araki Jun, Mifuji Rumi, Itani Toshio, Kuroda Makoto, Sato Hiroshi, Kaito Masahiko, Adachi Yukihiko
Abstract excerpt
BACKGROUND AND AIM: Numerous mutations of bilirubin uridine diphosphate-glucuronosyltransferase gene (UGT1A1) have been reported in patients with familial unconjugated hyperbilirubinemia. The UGT1A1 mutation appears to be considerably different among ethnic groups. To clarify the incidence of this gene mutation in the Japanese population, the presence of UGT1A1 mutation was investigated in a group of Japanese...
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