Article
Brain-derived neurotrophic factor gene variation influences cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol concentrations in healthy volunteers.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Dec 2008
Jönsson Erik G, Saetre Peter, Edman-Ahlbom Bodil, Sillén Anna, Gunnar Agneta, Andreou Dimitrios, Agartz Ingrid, Sedvall Göran, Hall Håkan, Terenius Lars
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) has been shown to influence monoamine transmitter synthesis, metabolism and release. We investigated possible relationships between four BDNF gene polymorphisms and cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA), and 3-methoxy-4-hydroxyphenylglycol (MHPG) in healthy volunteers (n = 132). All BDNF polymorphisms (270...
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