Article
Monoamine metabolites level in CSF is related to the 5-HTT gene polymorphism in treatment-resistant depression.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Oct 2007
Kishida Ikuko, Aklillu Eleni, Kawanishi Chiaki, Bertilsson Leif, Agren Hans
Abstract excerpt
The serotonin (5-hydroxytryptamine) transporter (5-HTT) is considered to affect the pathogenesis of mood disorders. Large number of genetic association studies between 5-HTT functional polymorphisms and vulnerability of mood disorders and therapeutic response to antidepressants has been carried o...
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