Article
Meta-analysis of genome-wide linkage studies across autoimmune diseases.
European journal of human genetics : EJHG - 1 Feb 2009
Forabosco Paola, Bouzigon Emmanuelle, Ng Mandy Y, Hermanowski Jane, Fisher Sheila A, Criswell Lindsey A, Lewis Cathryn M
Abstract excerpt
Autoimmune diseases are chronic disorders initiated by a loss of immunologic tolerance to self-antigens. They cluster within families, and patients may be diagnosed with more than one disease, suggesting pleiotropic genes are involved in the aetiology of different diseases. To identify potential loci, which confer susceptibility to autoimmunity independent of disease phenotype, we pooled results from genome-wide...
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