Article
Genetic variation associated with cardiovascular risk in autoimmune diseases.
PloS one - 1 Jan 2017
Perrotti Pedro P, Aterido Adrià, Fernández-Nebro Antonio, Cañete Juan D, Ferrándiz Carlos, Tornero Jesús, Gisbert Javier P, Domènech Eugeni, Fernández-Gutiérrez Benjamín, Gomollón Fernando, García-Planella Esther, Fernández Emilia, Sanmartí Raimon, Gratacós Jordi, Martínez-Taboada Víctor Manuel, Rodríguez-Rodríguez Luís, Palau Núria, Tortosa Raül, Corbeto Mireia L, Lasanta María L, Marsal Sara, Julià Antonio
Abstract excerpt
Autoimmune diseases have a higher prevalence of cardiovascular events compared to the general population. The objective of this study was to investigate the genetic basis of cardiovascular disease (CVD) risk in autoimmunity. We analyzed genome-wide genotyping data from 6,485 patients from six autoimmune diseases that are associated with a high socio-economic impact. First, for each disease, we tested the...
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