Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA , CTLA-4 and PTPN22 : the shared genetic master-key to autoimmunity?

Expert reviews in molecular medicine - 17 Oct 2005

Brand Oliver, Gough Stephen, Heward Joanne

Abstract excerpt

Several genetic loci appear to be involved in susceptibility to autoimmune disease. Some loci are disease specific, whereas others appear to exert a general effect on the autoimmune disease process. Despite a large number of studies of many different diseases, consistent associations with multiple autoimmune disorders have been restricted to three gene regions: the human leukocyte antigen (HLA) class II region on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Antigens, Differentiation
Share to Autoimmune Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CTLA-4 Antigen

Share to Genetic Predisposition to Disease

Share to HLA Antigens

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Share to Protein Tyrosine Phosphatases

Source

Identifiers

PMID: 16229750
DOI: 10.1017/S1462399405009981

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA , CTLA-4 and PTPN22 : the shared genetic master-key to autoimmunity?PMID 16229750Read ↗

The role of PTPN22 in the pathogenesis of autoimmune diseases: A comprehensive review.Semantic proximity Read ↗

PTPN22: the archetypal non-HLA autoimmunity gene.Semantic proximity Read ↗

Innate and adaptive immune abnormalities underlying autoimmune diseases: the genetic connections.Semantic proximity Read ↗

Genetic Polymorphism of PTPN22 in Autoimmune Diseases: A Comprehensive Review.Semantic proximity Read ↗

[Genetics of autoimmune and collagen diseases].Semantic proximity Read ↗

Regulation of T Cell Signaling and Immune Responses by PTPN22.Semantic proximity Read ↗

The genetics of human autoimmune disease.Semantic proximity Read ↗

Recent advances in the genetics of autoimmune disease.Semantic proximity Read ↗

[Role of HLA genetic variants in autoimmune diseases].Semantic proximity Read ↗

The immunogenetic architecture of autoimmune disease.Semantic proximity Read ↗

The putative role of the C1858T polymorphism of protein tyrosine phosphatase PTPN22 gene in autoimmunity.Semantic proximity Read ↗

Protein tyrosine phosphatases in autoimmunity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.