Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interleukin and interleukin receptor gene polymorphisms and susceptibility to melanoma.

Melanoma research - 1 Oct 2008

Gu Fangyi, Qureshi Abrar A, Niu Tianhua, Kraft Peter, Guo Qun, Hunter David J, Han Jiali

Abstract excerpt

Genetic variation in immune-regulating components such as cytokines may lead to interindividual differences in immunosuppression response and susceptibility to melanoma. We evaluated the associations between genetic variants in five interleukins (IL) and IL receptor genes (IL-4, IL-4R, IL-6, IL-6R, and IL-10) and the risk of melanoma. Twenty-five single nucleotide polymorphisms (SNPs) were selected that are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exons
Share to Interleukins
Share to Introns

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Melanoma

Share to Promoter Regions, Genetic

Share to Receptors, Interleukin

Share to Receptors, Interleukin-6

Share to Skin Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 18781131
DOI: 10.1097/CMR.0b013e32830658b2
PMCID: PMC2643877

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interleukin and interleukin receptor gene polymorphisms and susceptibility to melanoma.PMID 18781131Read ↗

Influence of IL1B (rs16944) and IL1R2 (rs4141134) polymorphisms on aggressiveness and prognosis of cutaneous melanoma.Semantic proximity Read ↗

Genetic associations of the interleukin locus at 1q32.1 with clinical outcomes of cutaneous melanoma.Semantic proximity Read ↗

Association of inherited variation in Toll-like receptor genes with malignant melanoma susceptibility and survival.Semantic proximity Read ↗

Genetic variants in interleukin genes are associated with breast cancer risk and survival in a genetically admixed population: the Breast Cancer Health Disparities Study.Semantic proximity Read ↗

Association of Common Genetic Polymorphisms with Melanoma Patient IL-12p40 Blood Levels, Risk, and Outcomes.Semantic proximity Read ↗

Interleukin genes and associations with colon and rectal cancer risk and overall survival.Semantic proximity Read ↗

Association of cytokine gene polymorphisms with malignant melanoma in Caucasian population.Semantic proximity Read ↗

Genetic variation in proinflammatory cytokines IL6, IL6R, TNF-region, and TNFRSF1A and risk of breast cancer.Semantic proximity Read ↗

Interleukin-1β Gene (IL-1B) rs16944 (-511 C > T) Promoter Polymorphism Is Associated with Cutaneous Melanoma Susceptibility, Stage, and Anatomical Localization in a Northern Italian Case-Control Study.Semantic proximity Read ↗

Cytokine gene single nucleotide polymorphisms and susceptibility to and prognosis in cutaneous malignant melanoma.Semantic proximity Read ↗

Identification of novel SNPs in the interleukin 6 receptor gene (IL6R).Semantic proximity Read ↗

Interleukin-1β Gene (IL1B) rs1143634 (+3954 C>T) Polymorphism and Cutaneous Melanoma Risk: An Observational Case-Control Study in Northeast Italy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.