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Article

Infection of Aedes albopictus and Aedes aegypti mosquitoes with dengue parent and progeny candidate vaccine viruses: a possible marker of human attenuation.

The American journal of tropical medicine and hygiene - 1 Aug 1991

Schoepp R J, Beaty B J, Eckels K H

Abstract excerpt

Dengue (DEN-1) and DEN-4 parent (P) and progeny candidate vaccine (CV) viruses were compared in their abilities to infect and to replicate in Aedes aegypti and Aedes albopictus mosquitoes. The DEN CV clones were temperature sensitive (ts) and had small plaque morphology. The DEN-1 and DEN-4 CV vi...

Topics

Aedes
Animals
Biomarkers
Dengue
Dengue Virus
Humans
Insect Vectors
Phenotype
Saliva
Temperature
Viral Plaque Assay
Viral Vaccines
Virus Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1877715
DOI: 10.4269/ajtmh.1991.45.202

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1877715-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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