Article
No requirement for localized Nudel protein expression in Drosophila embryonic axis determination.
Fly - 1 Jan 2000
Stein David, Cho Yong Suk, Zhang Zhenyu, Stevens Leslie M
Abstract excerpt
Drosophila embryonic dorsal-ventral polarity is defined by a maternally encoded signal transduction pathway. Gastrulation Defective, Snake, and Easter comprise a serine protease cascade that operates in the perivitelline space to generate active ligand for the Toll receptor, which resides in the embryonic membrane. Toll is activated only on the ventral side of the embryo. Spatial regulation of this pathway is...
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