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Article

Synthesis of the sulfate donor PAPS in either the Drosophila germline or somatic follicle cells can support embryonic dorsal-ventral axis formation.

Development (Cambridge, England) - 1 Apr 2007

Zhu Xianjun, Stevens Leslie M, Stein David

Abstract excerpt

The establishment of dorsal-ventral (DV) polarity in the Drosophila embryo depends upon a localized signal that is generated in the perivitelline space of the egg through the action of a serine proteolytic cascade. Spatial regulation of this pathway is determined by the expression of the pipe gene in a subpopulation of ventral follicle cells in the developing egg chamber. The Pipe protein exhibits homology to...

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Identifiers

PMID: 17344226
DOI: 10.1242/dev.003426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Synthesis of the sulfate donor PAPS in either the Drosophila germline or somatic follicle cells can support embryonic dorsal-ventral axis formation.PMID 17344226Read ↗

Spatially restricted expression of pipe in the Drosophila egg chamber defines embryonic dorsal-ventral polarity.Semantic proximity Read ↗

Drosophila pipe protein activity in the ovary and the embryonic salivary gland does not require heparan sulfate glycosaminoglycans.Semantic proximity Read ↗

Distinct functional specificities are associated with protein isoforms encoded by the Drosophila dorsal-ventral patterning gene pipe.Semantic proximity Read ↗

Slalom encodes an adenosine 3'-phosphate 5'-phosphosulfate transporter essential for development in Drosophila.Semantic proximity Read ↗

Windbeutel is required for function and correct subcellular localization of the Drosophila patterning protein Pipe.Semantic proximity Read ↗

The Drosophila dorsoventral determinant PIPE contains ten copies of a variable domain homologous to mammalian heparan sulfate 2-sulfotransferase.Semantic proximity Read ↗

Activation of Snake in a serine protease cascade that defines the dorsoventral axis is atypical and pipe-independent in Drosophila embryos.Semantic proximity Read ↗

No requirement for localized Nudel protein expression in Drosophila embryonic axis determination.Semantic proximity Read ↗

Essential roles of 3'-phosphoadenosine 5'-phosphosulfate synthase in embryonic and larval development of the nematode Caenorhabditis elegans.Semantic proximity Read ↗

Localized requirements for windbeutel and pipe reveal a dorsoventral prepattern within the follicular epithelium of the Drosophila ovary.Semantic proximity Read ↗

Mosaic analyses reveal the function of Drosophila Ras in embryonic dorsoventral patterning and dorsal follicle cell morphogenesis.Semantic proximity Read ↗

Two Golgi-resident 3'-Phosphoadenosine 5'-phosphosulfate transporters play distinct roles in heparan sulfate modifications and embryonic and larval development in Caenorhabditis elegans.Semantic proximity Read ↗

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