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Article

Distinct functional specificities are associated with protein isoforms encoded by the Drosophila dorsal-ventral patterning gene pipe.

Development (Cambridge, England) - 1 Aug 2009

Zhang Zhenyu, Zhu Xianjun, Stevens Leslie M, Stein David

Abstract excerpt

Spatially regulated transcription of the pipe gene in ventral cells of the Drosophila ovary follicle cell epithelium is a key event that specifies progeny embryo dorsal-ventral (DV) polarity. pipe encodes ten putative protein isoforms, all of which exhibit similarity to vertebrate glycosaminoglycan-modifying enzymes. Expression of one of the isoforms, Pipe-ST2, in follicle cells has previously been shown to be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19633171
DOI: 10.1242/dev.034413
PMCID: PMC2730406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Distinct functional specificities are associated with protein isoforms encoded by the Drosophila dorsal-ventral patterning gene pipe.PMID 19633171Read ↗

Spatially restricted expression of pipe in the Drosophila egg chamber defines embryonic dorsal-ventral polarity.Semantic proximity Read ↗

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Synthesis of the sulfate donor PAPS in either the Drosophila germline or somatic follicle cells can support embryonic dorsal-ventral axis formation.Semantic proximity Read ↗

No requirement for localized Nudel protein expression in Drosophila embryonic axis determination.Semantic proximity Read ↗

Localized requirements for windbeutel and pipe reveal a dorsoventral prepattern within the follicular epithelium of the Drosophila ovary.Semantic proximity Read ↗

Activation of Snake in a serine protease cascade that defines the dorsoventral axis is atypical and pipe-independent in Drosophila embryos.Semantic proximity Read ↗

Mosaic analyses reveal the function of Drosophila Ras in embryonic dorsoventral patterning and dorsal follicle cell morphogenesis.Semantic proximity Read ↗

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