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Article

Functional region mapping of HIV-2 Vpx protein.

Microbes and infection - 1 Oct 2008

Fujita Mikako, Otsuka Masami, Nomaguchi Masako, Adachi Akio

Abstract excerpt

To determine functional regions of HIV-2 Vpx, we analyzed a series of site-specific vpx-mutants for their growth potentials in lymphocytic cells and compared the results with those in macrophages. We found that amino acid residues important for virus growth in lymphocytic cells, in macrophages, and in both are clustered separately in Vpx. Through generation and characterization of new vpx-mutants, we further...

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Identifiers

PMID: 18771746
DOI: 10.1016/j.micinf.2008.08.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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