A promoter variant in the chitinase 3-like 1 gene is associated with serum YKL-40 level and personality trait.

doi:10.1016/j.neulet.2012.02.039

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Article

A promoter variant in the chitinase 3-like 1 gene is associated with serum YKL-40 level and personality trait.

Neuroscience letters - 4 Apr 2012

Yamamori Hidenaga, Hashimoto Ryota, Ohi Kazutaka, Yasuda Yuka, Fukumoto Motoyuki, Kasahara Emiko, Sekiyama Atsuo, Umeda-Yano Satomi, Okada Takeya, Iwase Masao, Kazui Hiroaki, Ito Akira, Takeda Masatoshi

Abstract excerpt

The chitinase 3-like 1 (CHI3L1) gene, a cellular survival factor against several environmental and psychosocial stresses, has been sown to be more highly expressed in the hippocampus and prefrontal cortex of patients with schizophrenia than unaffected individuals. We recently reported a significant association between schizophrenia and SNP rs4950928, which is located in the promoter region of the CHI3L1 gene, in...

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PMID: 22366530
DOI: 10.1016/j.neulet.2012.02.039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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