Article
A Preliminary Genetic Analysis of Complement 3 Gene and Schizophrenia.
PloS one - 1 Jan 2015
Ni Jianliang, Hu Shuangfei, Zhang Jiangtao, Tang Wenxin, Lu Weihong, Zhang Chen
Abstract excerpt
Complement pathway activation was found to occur frequently in schizophrenia, and complement 3 (C3) plays a major role in this process. Previous studies have provided evidence for the possible role of C3 in the development of schizophrenia. In this study, we hypothesized that the gene encoding C3 (C3) may confer susceptibility to schizophrenia in Han Chinese. We analyzed 7 common single nucleotide polymorphisms...
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