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Article

The role of aberrant transcription factor in the progression of chronic myeloid leukemia.

Leukemia & lymphoma - 1 Aug 2008

Zhang Sujiang

Abstract excerpt

Chronic myeloid leukemia (CML) is a hematopoietic stem cell disease with distinct biological and clinical features. The Philadelphia (Ph) chromosome and BCR/ABL fusion gene is the major cytogenetic and molecular marker of CML chronic phase. However, the molecular mechanisms of disease progression are not well known. Recent studies have shown that a several of transcription factors such as AML1, C/EBPalpha, HOX...

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Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

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Identifiers

PMID: 18766960
DOI: 10.1080/10428190802163305

Genes

BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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