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Article

Inactivation of clathrin heavy chain inhibits synaptic recycling but allows bulk membrane uptake.

The Journal of cell biology - 8 Sept 2008

Kasprowicz Jaroslaw, Kuenen Sabine, Miskiewicz Katarzyna, Habets Ron L P, Smitz Liesbet, Verstreken Patrik

Abstract excerpt

Synaptic vesicle reformation depends on clathrin, an abundant protein that polymerizes around newly forming vesicles. However, how clathrin is involved in synaptic recycling in vivo remains unresolved. We test clathrin function during synaptic endocytosis using clathrin heavy chain (chc) mutants combined with chc photoinactivation to circumvent early embryonic lethality associated with chc mutations in...

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Source

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Identifiers

PMID: 18762582
DOI: 10.1083/jcb.200804162
PMCID: PMC2528586

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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