Article
Clathrin-mediated endocytic signals are required for the regeneration of, as well as homeostasis in, the planarian CNS.
Development (Cambridge, England) - 1 May 2007
Inoue Takeshi, Hayashi Tetsutaro, Takechi Katsuaki, Agata Kiyokazu
Abstract excerpt
Planarians have a well-organized central nervous system (CNS), including a brain, and can regenerate the CNS from almost any portion of the body using pluripotent stem cells. In this study, to identify genes required for CNS regeneration, genes expressed in the regenerating CNS were systematically cloned and subjected to functional analysis. RNA interference (RNAi) of the planarian clathrin heavy chain (DjCHC)...
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