Article
Phenotype of blasts in chronic myeloid leukemia in blastic phase-Analysis of bone marrow trephine biopsies and correlation with cytogenetics.
Leukemia research - 1 Mar 2009
Reid Alistair G, De Melo Valeria A, Elderfield Kay, Clark Ian, Marin David, Apperley Jane, Naresh Kikkeri N
Abstract excerpt
We identified different phenotypic subsets among 62 cases of chronic myeloid leukemia (CML) in blast crisis (BC) (26% B-lymphoblastic, and 74% various myeloblastic subsets) on bone marrow trephines and correlated the blast-phenotype with cytogenetics. Five of myeloid-BC had an associated 3q26 abnormality and two of these showed a megakaryoblastic-phenotype. While myeloid-BC was associated with additional copies...
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