Article
Immunophenotypic and genotypic characteristics of chronic myelogenous leukemia in blast crisis.
Zhonghua yi xue za zhi = Chinese medical journal; Free China ed - 1 Nov 2000
Yen C C, Liu J H, Wang W S, Fan F S, Chiou T J, Tai C J, Yang M H, Chao T C, Hsiao L T, Chen P M
Abstract excerpt
BACKGROUND: Chronic myelogenous leukemia (CML) may transform into blast crisis (BC) if not properly treated. Among patients with transformation, 20% to 30% will develop BC with lymphoid-associated antigens (Ly-BC), and the remaining cases with myeloid-associated antigens (My-BC) or with both (Mix-BC). In this study, we investigated the lineage of blast cells in CML-BC using immunophenotypic and genetic analyses...
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