Association of PARL rs3732581 genetic variant with insulin levels, metabolic syndrome and coronary artery disease.

doi:10.1007/s00439-008-0552-2

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Article

Association of PARL rs3732581 genetic variant with insulin levels, metabolic syndrome and coronary artery disease.

Human genetics - 1 Oct 2008

Powell Brenda L, Wiltshire Steven, Arscott Gillian, McCaskie Pamela A, Hung Joseph, McQuillan Brendan M, Thompson Peter L, Carter Kim W, Palmer Lyle J, Beilby John P

Abstract excerpt

PARL (presenilin-associated rhomboid-like) is a mitochondrial protein involved in mitochondrial membrane remodelling, and maps to a quantitative trait locus (3q27) associated with metabolic traits. Recently the rs3732581 (Leu262Val) variant was found to be associated with increased levels of plasma insulin, a finding not replicated in a larger cohort. The aim of the current study was to investigate the...

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PMID: 18758826
DOI: 10.1007/s00439-008-0552-2

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PARL
CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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