Article
Association of a polymorphism in the lipin 1 gene with systolic blood pressure in men.
American journal of hypertension - 1 May 2008
Ong K L, Leung Raymond Y H, Wong Louisa Y F, Cherny Stacey S, Sham P C, Lam T H, Lam Karen S L, Cheung Bernard M Y
Abstract excerpt
BACKGROUND: Lipin 1 plays a role in abdominal obesity, insulin resistance, and hypertriglyceridemia. The gene is located at 2p25.1, a susceptibility locus for hypertension. We studied the association of tagging single-nucleotide polymorphisms (SNPs) in the lipin 1 (LPIN1) gene with hypertension and blood pressure. METHODS: Twelve tagging SNPs from the HapMap database were genotyped using Sequenom MassArray in 268...
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