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The influence of carbon sources on recombinant-human- growth-hormone production by Pichia pastoris is dependent on phenotype: a comparison of Muts and Mut+ strains.

Biotechnology and applied biochemistry - 1 Mar 2009

Orman Mehmet Ali, Calik Pinar, Ozdamar Tunçer H

Abstract excerpt

The influence of carbon sources on rhGH (recombinant human growth hormone) production by two Pichia pastoris strains having different methanol utilization phenotypes (P. pastoris-hGH-Mut(+) and P. pastoris-hGH-Mut(s)) was investigated using batch bioreactors. The effect of methanol concentration (C(MeOH)) in defined and complex media, and further glycerol/methanol mixed defined media, was analysed systematically...

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Source

Identifiers

PMID: 18754757
DOI: 10.1042/BA20080057

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AOX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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