Article
Maximizing recombinant human serum albumin production in a Mut(s) Pichia pastoris strain.
Biotechnology progress - 1 Jan 2000
Mallem Muralidhar, Warburton Shannon, Li Fang, Shandil Ishaan, Nylen Adam, Kim Sehoon, Jiang Youwei, Meehl Michael, d'Anjou Marc, Stadheim Terrance A, Choi Byung-Kwon
Abstract excerpt
Human serum albumin (HSA) is a cysteine rich molecule that is most abundant in human blood plasma. To remain viable in the market due to lower marketing costs for HSA, it is important to produce a large quantity in an economical manner by recombinant technology. The objective of this study was to maximize recombinant HSA (rHSA) production using a Mut(s) Pichia pastoris strain by fermentation process optimization....
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