Article
Expression of unique chimeric human papilloma virus type 16 (HPV‐16) L1‐L2 proteins in Pichia pastoris and Hansenula polymorpha
30 Apr 2018
Abstract excerpt
Abstract Cervical cancer is ranked the fourth most common cancer in women worldwide. Despite two prophylactic vaccines being commercially available, they are unaffordable for most women in developing countries. We compared the optimized expression of monomers of the unique HPV type 16 L1‐L2 chimeric protein (SAF) in two yeast strains of Pichia pastoris, KM71 (Muts) and GS115 (Mut+), with Hansenula polymorpha NCYC...
