Article
Chronic myelomonocytic leukemia with nucleophosmin (NPM1) mutation.
European journal of haematology - 1 Jan 2016
Peng Jie, Zuo Zhuang, Fu Bin, Oki Yasuhiro, Tang Guilin, Goswami Maitrayee, Priyanka Priyanka, Muzzafar Tariq, Medeiros L Jeffrey, Luthra Rajyalakshmi, Wang Sa A
Abstract excerpt
Nucleophosmin (NPM1) mutations in chronic myelomonocytic leukemia (CMML) are extremely uncommon, and the clinicopathologic features of these neoplasms are poorly characterized. Over a 10-yr interval, NPM1 mutation analysis was performed in 152 CMML at our institution. NPM1 mutations were identified in 8 (5.3%) patients, five men and three women, with a median age of 72 yr (range, 27-87). In all patients, the bone...
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