Article
Nucleophosmin mutations in de novo acute myeloid leukemia: the age-dependent incidences and the stability during disease evolution.
Cancer research - 15 Mar 2006
Chou Wen-Chien, Tang Jih-Luh, Lin Liang-In, Yao Ming, Tsay Woei, Chen Chien-Yuan, Wu Shang-Ju, Huang Chi-Fei, Chiou Rong-Jing, Tseng Mei-Hsuan, Lin Dong-Tsamn, Lin Kai-Hsin, Chen Yao-Chang, Tien Hwei-Fang
Abstract excerpt
Nucleophosmin (NPM) mutations have been found in a significant proportion of adults with de novo acute myeloid leukemia (AML), especially in those of a normal karyotype. These results provide a basis for studies of the pathogenesis in this specific subgroup of AML. In this study, NPM mutations we...
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