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Article

Obesity enhances gastrointestinal tumorigenesis in Apc-mutant mice.

International journal of obesity (2005) - 1 Nov 2008

Gravaghi C, Bo J, Laperle K M D, Quimby F, Kucherlapati R, Edelmann W, Lamprecht S A

Abstract excerpt

Epidemiological evidence indicates a link between obesity and human colon cancer. A putative association between obesity and colon tumorigenesis has been explored experimentally using chemical carcinogens administered to obese rodents. The main objective of this study was to generate a new mouse...

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Share to Cell Transformation, Neoplastic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18725892
DOI: 10.1038/ijo.2008.149

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18725892-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Obesity enhances gastrointestinal tumorigenesis in Apc-mutant mice.PMID 18725892Read ↗

Diet- and Genetically-induced Obesity Produces Alterations in the Microbiome, Inflammation and <i>Wnt </i>Pathway in the Intestine of Apc<sup>+/1638N</sup> Mice: Comparisons and ContrastsSemantic proximity Read ↗

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