Article
Expression of SV40 T antigen under control of rabbit uteroglobin promoter in transgenic mice.
The American journal of physiology - 1 Aug 1991
DeMayo F J, Finegold M J, Hansen T N, Stanley L A, Smith B, Bullock D W
Abstract excerpt
The rabbit uteroglobin gene is expressed in the lungs and reproductive tracts of male and female rabbits. To examine whether the promoter region of the uteroglobin gene could be used to target a heterologous gene to the lungs of transgenic mice, a fusion gene consisting of 3.3 kb of the 5'-flanking region of the rabbit uteroglobin gene and the large T antigen gene of the SV40 virus was constructed and...
Topics
- Animals
- Antigens, Polyomavirus Transforming
- Antigens, Viral, Tumor
- Blotting, Northern
- Bronchial Neoplasms
- Female
- Immunohistochemistry
- Lung
- Lung Neoplasms
- Male
- Mice
