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Article

Tissue-specific expression of p53 in transgenic mice is regulated by intron sequences.

Molecular carcinogenesis - 1 Jan 1991

Lozano G, Levine A J

Abstract excerpt

Transgenic mice were produced harboring the p53 murine cDNA clone regulated by the SV40 enhancer-promoter region 5' to the cDNA and the small t antigen splice sites, and poly(A) addition signals 3' to the cDNA. This construction was not expressed in these mice. The presence of several murine p53 introns in the cDNA, however, permitted expression of the transgene mRNA in several tissues of transgenic mice. The...

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Source

Identifiers

PMID: 1848986
DOI: 10.1002/mc.2940040103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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